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Invitrogen™ CNGB1 Polyclonal Antibody
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Catalog No. PIPA5101543
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100 μL
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PIPA5101543 100 μL
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Catalog No. PIPA5101543 Supplier Invitrogen™ Supplier No. PA5101543
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CNGB1.

Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. GARPs are characterized by six repeated motifs of: V V E K K N/E E. These repeat motifs help form an alpha-helix structure. The function(s) of GARP have not been fully characterized, but studies have suggested that GARP helps limit cGMP turnover by inhibiting phosphodiesterase activity. To date, there have been two splice variants characterized: GARP1 (full-length GARP) and GARP2 (truncated GARP). GARP also interacts with part of the larger cytoplasmic domain of the beta-subunit of the cyclic GMP-gated channel found in the plasma membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNGB1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CNGB1
Gene Accession No. Q14028
Gene Alias 240 kDa protein of rod photoreceptor CNG-channel; 240K protein of rod photoreceptor cng-channel; CNCG2; CNCG3L; CNCG4; cng channel; CNG channel 4; CNG channel beta-1; CNG4; CNG-4; CNG4c protein; CNGB1; CNGB1B; cyclic nucleotide gated channel beta 1; cyclic nucleotide gated channel subunit beta 1; cyclic nucleotide-gated cation channel 4; Cyclic nucleotide-gated cation channel beta-1; cyclic nucleotide-gated cation channel gamma; Cyclic nucleotide-gated cation channel modulatory subunit; cyclic nucleotide-gated channel beta subunit 1; cyclic nucleotide-gated channel beta subunit 1c; cyclic nucleotide-gated channel beta subunit 1d; cyclic nucleotide-gated channel beta subunit 1e; cyclic nucleotide-gated channel beta-1; GAR1; GARP; GARP2; glutamic acid-rich protein; glutamic-acid-rich protein; Gm1959; RCNC2; RCNCb; RCNCbeta; RP45; splice variant; tGARP; glutamic acid rich protein; truncated rod photoreceptor cGMP-gated channel beta-subunit
Gene Symbols CNGB1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CNGB1(Accession Q14028), corresponding to amino acid residues V917-D967.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1258, 333329, 83686
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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