Invitrogen™ CNOT2 Monoclonal Antibody (OTI5A12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527037

Catalog No. PIMA527037

Description

CNOT2 Monoclonal Antibody for Western Blot, IHC (P)

CCR4-NOT Transcription Complex 2 (CNOT2) is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. CNOT2 is required for the CCR4-NOT complex structural integrity. It can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. CNOT2 is involved in the maintenance of embryonic stem (ES) cell identity. (UniProt).

Specifications

• Antigen: CNOT2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9NZN8
• Gene Symbols: Cnot2
• Immunogen: Full length human recombinant protein of CNOT2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI5A12
• Conjugate: Unconjugated
• Gene: Cnot2
• Gene Alias: 2600016M12Rik; 2810470K03Rik; AA537049; AA959607; AW557563; C79650; CCR4-associated factor 2; CCR4-NOT transcription complex subunit 2; CCR4-NOT transcription complex, subunit 2; CDC36; CNOT2; HSPC131; MSTP046; negative regulator of transcription 2; NOT2; NOT2H
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4848
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid