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Invitrogen™ CNOT2 Polyclonal Antibody
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Catalog No. PIPA566949
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100 μL
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PIPA566949 100 μL
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Catalog No. PIPA566949 Supplier Invitrogen™ Supplier No. PA566949
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DGSENVTGLDL SDFPALADRN RREGSGNPTP LINPLAGRAP YVGMVTKPAN EQSQDFSIHN EDFPALPGSS YKDPT Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.

CCR4-NOT Transcription Complex 2 (CNOT2) is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. CNOT2 is required for the CCR4-NOT complex structural integrity. It can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. CNOT2 is involved in the maintenance of embryonic stem (ES) cell identity. (UniProt).
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNOT2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Cnot2
Gene Accession No. Q9NZN8
Gene Alias 2600016M12Rik; 2810470K03Rik; AA537049; AA959607; AW557563; C79650; CCR4-associated factor 2; CCR4-NOT transcription complex subunit 2; CCR4-NOT transcription complex, subunit 2; CDC36; CNOT2; HSPC131; MSTP046; negative regulator of transcription 2; NOT2; NOT2H
Gene Symbols Cnot2
Host Species Rabbit
Immunogen Recombinant Human CNOT2. Recombinant protein control fragment (Product #RP-105435).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4848
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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