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Invitrogen™ CNOT3 Polyclonal Antibody
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Catalog No. PIPA530248
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100 μL
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Catalog No. Quantity
PIPA530248 100 μL
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Catalog No. PIPA530248 Supplier Invitrogen™ Supplier No. PA530248
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, IMR32, Jurkat, HeLa. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (92%), Rabbit (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNOT3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.63 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene CNOT3
Gene Accession No. O75175
Gene Alias A930039N10Rik; CCR4-associated factor 3; CCR4-NOT transcription complex subunit 3; CCR4-NOT transcription complex, subunit 3; CNOT3; KIAA0691; LENG2; Leukocyte receptor cluster member 2; Not3; NOT3 (negative regulator of transcription 3, yeast) homolog; NOT3H
Gene Symbols CNOT3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human CNOT3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4849
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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