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Invitrogen™ CNOT6 Polyclonal Antibody
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Catalog No. PIPA569096
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100 μL
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PIPA569096 100 μL
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Catalog No. PIPA569096 Supplier Invitrogen™ Supplier No. PA569096
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%.

Poly(A) nuclease with 3'-5' RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA. The increase of ligand-dependent ESR1-mediated transcription is much smaller, if any. Mediates cell proliferation and cell survival and prevents cellular senescence.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNOT6
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene CNOT6
Gene Accession No. Q9ULM6
Gene Alias carbon catabolite repression 4 protein; carbon catabolite repressor protein 4 homolog; Ccr4; CCR4 carbon catabolite repression 4-like; Ccr4a; CCR4-NOT transcription complex subunit 6; CCR4-NOT transcription complex, subunit 6; Cnot6; Cytoplasmic deadenylase; Kiaa1194; LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 6; RGD1310783
Gene Symbols CNOT6
Host Species Rabbit
Immunogen synthetic peptide directed towards the N terminal region of human CNOT6.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57472
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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