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Invitrogen™ CNOT6L Polyclonal Antibody
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Catalog No. PIPA525131
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400 μL
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Catalog No. Quantity
PIPA525131 400 μL
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Catalog No. PIPA525131 Supplier Invitrogen™ Supplier No. PA525131
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with mouse and Xenopus based on sequence homology.

Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA. Its mRNA deadenylase activity can be inhibited by TOB1. Mediates cell proliferation and cell survival and prevents cellular senescence. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNOT6L
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CNOT6L
Gene Accession No. Q96LI5
Gene Alias Carbon catabolite repressor protein 4 homolog B; CCR4b; CCR4-NOT transcription complex subunit 6 like; CCR4-NOT transcription complex subunit 6-like; CCR4-NOT transcription complex, subunit 6-like; CNOT6L
Gene Symbols CNOT6L
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human CNO6L.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 246175
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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