Invitrogen™ CNPY3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596600

Catalog No. PIPA596600

Description

Immunogen sequence: GPSQAGAEEN DWVRLPSKCE VCKYVAVELK SAFEETGKTK EVIGTGYGIL DQKASGVKYT KSDLRLIEVT ETICKRLLDY SLHKERTGSN RFAKGMSETF ETLHNLVHKG VKVVMDIPYE LWNETSAEVA DLKKQCDVLV EEFEEVIEDW YRNHQEEDLT EFLCANHVLK GKDTSCLAEQ WSGKKGDTAA LGGKKSKKKS SRAKAAGGRS SSSKQRKELG GLEGDPSPEE DEGIQKASPL THSPPDEL; Positive Samples: HepG2, MCF7, THP-1, HL-60, U-937; Cellular Location: Endoplasmic reticulum.

PRAT4A is a novel protein belonging to the canopy family with a saposin B-type domain. It is an accessory molecule required for microbial recognition by Toll-like receptor (TLR), and mediates TLR dependent immune responses. Though the exact function of PRAT4A is still unknown, reports suggest that it is associated with the immature form of TLR4 and regulates the cell surface expression of this TLR. PRAT4A, a secreted protein, also has a role in TLR4 maturation and glycosylation. PRATA4 is usually present in endoplasmic reticulum and plays an active role in regulating the subcellular distribution and response of multiple TLRs and is required for both innate and adaptive immune responses.

Specifications

• Antigen: CNPY3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CNPY3
• Gene Alias: 1600025D17Rik; 2410050O22Rik; AI413153; CAG repeat containing; CAG/CTG 5; CAG4A; canopy 3 homolog; canopy 3 homolog (zebrafish); canopy FGF signaling regulator 3; CNPY3; CTG repeat protein 4a; CTG4A; ERDA5; expanded repeat-domain protein CAG/CTG 5; HSPC084; Prat4a; protein associated with TLR4; protein associated with Toll-like receptor 4A; protein canopy homolog 3; Tnrc5; trinucleotide repeat containing 5; trinucleotide repeat-containing gene 5 protein; Unknown (protein for MGC:140466); UNQ1934/PRO4409
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10695, 72029
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.49 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BT09, Q9DAU1
• Gene Symbols: CNPY3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 31-278 of human CNPY3 (NP_0065772).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov