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CNR-2/PCDHA6 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984060
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50-198-4060 100 μL
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Catalog No. 50-198-4060 Supplier Bioss Supplier No. BS1711R
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Description

Rabbit Polyclonal Antibody

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Specifications

Antigen CNR-2/PCDHA6
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PCDHA6
Gene Accession No. Q9UN73
Gene Alias cadherin-related neuronal receptor 2; cadherin-related neuronal receptor 6; CNR; Cnr2; CNRN2; CNRS2; Crnr2; KIAA0345-like 8; PCDHA6; PCDH-ALPHA6; PCDH-alpha-6; protocadherin alpha 6; Protocadherin alpha-6; rCNRv06
Gene Symbols PCDHA6
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CNR-2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56142
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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