Invitrogen™ CNR2 Recombinant Rabbit Monoclonal Antibody (13H43L20)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 703485

Catalog No. 70-348-5

Description

This antibody is predicted to react with Rat, Bovine.

Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.

Specifications

• Antigen: CNR2
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P34972, P47936
• Gene Symbols: CNR2
• Immunogen: Peptides corresponding to human CNR2 [1) aa341-aa360, 2) aa5-aa25, 3) aa2-25].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: 13H43L20
• Conjugate: Unconjugated
• Gene: CNR2
• Gene Alias: Cannabinoid Receptor 2; cannabinoid receptor 2 (macrophage); CB2; CB-2; CB2 receptor; CB2A; CB2B; CB2C; CB2R; CB2-R; CNR2; CNR2C; CNR3; CX5; HCB2; HGNC:2160; OTTHUMP00000044841; peripheral cannabinoid receptor; rCB2; RP11-4M23.1; testis-dominant CNR2 isoform CB2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1269, 12802
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov