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Invitrogen™ CNTF Polyclonal Antibody
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Catalog No. PIPA579056
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100 μg
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PIPA579056 100 μg
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Catalog No. PIPA579056 Supplier Invitrogen™ Supplier No. PA579056
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat PC-12 whole cell, rat NRK whole cell, rat RH-35 whole cell, rat brain tissue, rat liver tissue, rat spleen tissue, rat testis tissue. IHC: mouse brain tissue, rat brain tissue.

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNTF
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide
Gene CNTF
Gene Accession No. P20294, P51642
Gene Alias AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF
Gene Symbols CNTF
Host Species Rabbit
Immunogen E.coli-derived rat CNTF recombinant protein (Position: A2-M200).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12803, 25707
Target Species Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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