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Invitrogen™ CNTF Polyclonal Antibody
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Catalog No. PIPA130522
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50 μg
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PIPA130522 50 μg
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Catalog No. PIPA130522 Supplier Invitrogen™ Supplier No. PA130522
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Rabbit Polyclonal Antibody

PA1-30522 detects CNTF from rat samples.

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
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Specifications

Antigen CNTF
Applications ELISA, Functional Assay, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CNTF
Gene Accession No. P20294, P51642
Gene Alias AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF
Gene Symbols CNTF
Host Species Rabbit
Immunogen Recombinant rat CNTF.
Purification Method Affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12803, 25707
Target Species Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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