CNTF Receptor alpha Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-3521	100 μL

Catalog No. 50-198-3521 Supplier Bioss Supplier No. BS1516R

Description

Rabbit Polyclonal Antibody

This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.

Specifications

• Antigen: CNTF Receptor alpha
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Cntfr
• Gene Accession No.: P26992
• Gene Alias: ciliary neurotrophic factor receptor; ciliary neurotrophic factor receptor alpha; Ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR; CNTFR alpha; Cntfralpha; CNTFR-alpha; LOC100349367; MGC1774
• Gene Symbols: Cntfr
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human CNTFR Alpha.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1271
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG