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Invitrogen™ CNTFR Polyclonal Antibody
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Catalog No. PIPA518622
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100 μg
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Catalog No. Quantity
PIPA518622 100 μg
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Catalog No. PIPA518622 Supplier Invitrogen™ Supplier No. PA518622
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with canine, human and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNTFR
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Cntfr
Gene Accession No. O88507
Gene Alias ciliary neurotrophic factor receptor; ciliary neurotrophic factor receptor alpha; ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; Cntfr; CNTFR alpha; CNTFRALPHA; CNTFR-alpha; MGC1774
Gene Symbols Cntfr
Host Species Goat
Immunogen Synthetic peptide sequence (CRSNTYPKGFY) corresponding to the internal amino acids of CNTFR (aa 116-127).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12804
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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