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Invitrogen™ CNTFR Polyclonal Antibody
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Catalog No. PIPA597601
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100 μg
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Catalog No. Quantity
PIPA597601 100 μg
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Catalog No. PIPA597601 Supplier Invitrogen™ Supplier No. PA597601
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Description

Rabbit Polyclonal Antibody

CNTFR Polyclonal Antibody for Western Blot, IHC (P), ICC/IF, ELISA

This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNTFR
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Cntfr
Gene Accession No. P26992
Gene Alias ciliary neurotrophic factor receptor; ciliary neurotrophic factor receptor alpha; ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; Cntfr; CNTFR alpha; CNTFRALPHA; CNTFR-alpha; MGC1774
Gene Symbols Cntfr
Host Species Rabbit
Immunogen Recombinant Human Ciliary neurotrophic factor receptor subunit alpha protein (106-342AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1271
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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