Invitrogen™ CNTNAP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568409

Catalog No. PIPA568409

Description

Predicted to react with Mouse and Rat samples.

CNTNAP1 was initially identified as a 190-kDa protein associated with the contactin-PTPRZ1 complex. The 1, 384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein, ' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. The gene product was initially identified as a 190-kDa protein associated with the contactin-PTPRZ1 complex. The 1, 381-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein, ' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Specifications

• Antigen: CNTNAP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cntnap1
• Gene Alias: AI841080; Caspr; caspr1; CNTNAP; CNTNAP1; contactin associated protein 1; contactin associated protein-like 1; contactin-associated protein 1; LOW QUALITY PROTEIN: contactin-associated protein 1; MHDNIV; NCP1; neurexin 4; neurexin 4 (contactin associated protein); neurexin IV; Neurexin-4; NRXN4; p190; paranodin; shm
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 53321, 84008, 8506
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O54991, P78357, P97846
• Gene Symbols: Cntnap1
• Immunogen: Synthetic peptide corresponding to residues near the C terminal of human CNTNAP1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG