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Invitrogen™ Glypican 3 (Codrituzumab Biosimilar) Recombinant Human Monoclonal Antibody
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Catalog No. PIMA542002
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100 μg
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PIMA542002 100 μg
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Catalog No. PIMA542002 Supplier Invitrogen™ Supplier No. MA542002
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Description

Human Recombinant Monoclonal Antibody

Endotoxin level <0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt. This product is a Humanized mouse antibody.

GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Glypican 3 (Codrituzumab Biosimilar)
Applications ELISA, Flow Cytometry
Classification Recombinant Monoclonal
Concentration 1.1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene GPC3
Gene Accession No. P51654
Gene Alias defective in Simpson-Golabi-Behmel overgrowth syndrome; DGSX; glypican 3; glypican proteoglycan 3; glypican-3; Glypican-3 alpha subunit; Glypican-3 beta subunit; Gpc3; GTR22; GTR2-2; heparan sulphate proteoglycan; intestinal protein OCI-5; MXR7; OCI5; OCI-5; proteoglycan GPC3; SDYS; secreted glypican-3; SGB; SGBS; SGBS1
Gene Symbols GPC3
Host Species Human
Immunogen Human GPC3.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2719
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
Target Molecule Chemical
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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