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Invitrogen™ Cofilin Polyclonal Antibody
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Catalog No. PIPA124931
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50 μL
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Catalog No. Quantity
PIPA124931 50 μL
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Catalog No. PIPA124931 Supplier Invitrogen™ Supplier No. PA124931
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, PC-12, NIH3T3, MDCK. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cofilin
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 11.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene CFL1
Gene Accession No. P18760, P23528, P45592
Gene Alias 18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18
Gene Symbols CFL1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to human cofilin sequence, (amino acids 154-166) with N-terminal cysteine added, conjugated to KLH.
Purification Method IgG fraction
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1072, 12631, 29271, 476022
Target Species Human, Mouse, Rat, Canine
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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