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Invitrogen™ Cofilin Polyclonal Antibody
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Catalog No. PIPA524628
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400 μL
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Catalog No. Quantity
PIPA524628 400 μL
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Catalog No. PIPA524628 Supplier Invitrogen™ Supplier No. PA524628
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, chicken, porcine, non-human primate, rat and Xenopus based on sequence homology.

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cofilin
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CFL1
Gene Accession No. P18760, P23528
Gene Alias 18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18
Gene Symbols CFL1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 70-98 amino acids from the central region of human CFL1.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1072, 12631
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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