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Invitrogen™ COG2 Polyclonal Antibody
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Catalog No. PIPA5109567
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100 μL
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PIPA5109567 100 μL
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Catalog No. PIPA5109567 Supplier Invitrogen™ Supplier No. PA5109567
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MEKSRMNLPK GPDTLCFDKD EFMKEDFDVD HFVSDCRKRV QLEELRDDLE LYYKLLKTAM VELINKDYAD FVNLSTNLVG MDKALNQLSV PLGQLREEVL SLRSSVSEGI RAVDERMSKQ EDIRKKKMCV LRLIQVIRSV EKIEKILNSQ SSKETSALEA SSPLLTGQIL ERIATEFNQL QFHAVQSKGM PLLDKVRPRI AGITAMLQQS LEGLLLEGLQ TSDVDIIRHC LRTYATIDKT RDAEALVGQV LVKPYIDEVI IEQFVESHPN GLQVMYNKLL.

The structure and function of the Golgi apparatus is controlled by a number of multi-protein complexes that are involved in glycosylation reactions and vesicular transport. The conserved oligomeric Golgi (COG) complex consists of three subcomplexes, termed LDLC, SEC34 and GTT (Golgi transport complex), all of which contain proteins necessary for proper Golgi operation. COG2 (conserved oligomeric Golgi complex subunit 2), also known as LDLC, is a 730 amino acid component of the COG complex. Localized to the cytoplasmic side of the Golgi apparatus, COG2 is required for proper Golgi morphology and function, specifically playing a role in Golgi ribbon formation and vesicular transport. Abnormal COG2 function may cause cell death, suggesting that COG2 is an important factor in cell viability.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COG2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Cog2
Gene Accession No. Q14746, Q921L5
Gene Alias 1190002B08Rik; 2700012E02Rik; brefeldin A-sensitive, peripheral Golgi protein; C86089; COG 2; COG complex subunit 2; COG2; Component of oligomeric Golgi complex 2; conserved oligomeric Golgi complex protein 2; conserved oligomeric Golgi complex subunit 2; LDLC; low density lipoprotein receptor defect C complementing; low density lipoprotein receptor defect C-complementing protein; Transcript ch4822
Gene Symbols Cog2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human COG2 (NP_031383.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22796, 690961, 76332
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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