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Invitrogen™ Coilin Polyclonal Antibody
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Catalog No. PIPA5110950
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100 μL
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PIPA5110950 100 μL
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Catalog No. PIPA5110950 Supplier Invitrogen™ Supplier No. PA5110950
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NRSTDNQRQQ QLNDVVKNSS TIIQNPVETP KKDYSLLPLL AAAPQVGEKI AFKLLELTSS YSPDVSDYKE GRILSHNPET QQVDIEILSS LPALREPGKF DLVYHNENGA EVVEYAVTQE SKITVFWKEL IDPRLIIESP SNTSSTEPA Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 82%.

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Coilin
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene COIL
Gene Accession No. P38432
Gene Alias C79982; CLN80; COIL; Coilin; coilin p80; hypothetical protein LOC507580; LOW QUALITY PROTEIN: coilin; nuclear phosphoprotein of Cajal body; p80; p80-coilin; wu:fb08h11
Gene Symbols COIL
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human Coilin. Recombinant protein control fragment (Product #RP-105782).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8161
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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