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Invitrogen™ Coilin Polyclonal Antibody
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Catalog No. PIPA5117048
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100 μL
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PIPA5117048 100 μL
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Catalog No. PIPA5117048 Supplier Invitrogen™ Supplier No. PA5117048
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Description

Rabbit Polyclonal Antibody

Positive Samples: MCF7, HepG2, 293T, Rat testis Immunogen sequence: KLGFSLTPSK GKTSGTTSSS SDSSAESDDQ CLMSSSTPEC AAGFLKTVGL FAGRGRPGPG LSSQTAGAAG WRRSGSNGGG QAPGASPSVS LPASLGRGWG REENLFSWKG AKGRGMRGRG RGRGHPVSCV VNRSTDNQRQ QQLNDVVKNS STIIQNPVET PKKDYSLLPL LAAAPQVGEK IAFKLLELTS SYSPDVSDYK EGRILSHNPE TQQVDIEILS SLPALREPGK FDLVYHNENG AEVVEYAVTQ ESKITVFWKE LIDPRLIIES PSNTSSTEPA.

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Coilin
Applications ELISA, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 3.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene COIL
Gene Accession No. P38432, Q5SU73
Gene Alias C79982; CLN80; COIL; Coilin; coilin p80; hypothetical protein LOC507580; LOW QUALITY PROTEIN: coilin; nuclear phosphoprotein of Cajal body; p80; p80-coilin; wu:fb08h11
Gene Symbols COIL
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human Coilin (NP_0046361).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12812, 50998, 8161
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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