Invitrogen™ Coilin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100038

Catalog No. PIPA5100038

Description

Antibody detects endogenous levels of total Coilin.

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

Specifications

• Antigen: Coilin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COIL
• Gene Alias: C79982; CLN80; COIL; Coilin; coilin p80; hypothetical protein LOC507580; LOW QUALITY PROTEIN: coilin; nuclear phosphoprotein of Cajal body; p80; p80-coilin; wu:fb08h11
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12812, 50998, 8161
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P38432, Q5SU73
• Gene Symbols: COIL
• Immunogen: A synthesized peptide derived from human COIL(Accession P38432), corresponding to amino acid residues G371-H421.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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