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Invitrogen™ COL11A2 Polyclonal Antibody
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Catalog No. PIPA577258
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PIPA577258 100 μL
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Catalog No. PIPA577258 Supplier Invitrogen™ Supplier No. PA577258
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COL11A2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene COL11A2
Gene Accession No. P13942, Q64739
Gene Alias COL11A2; Collagen alpha-2(XI) chain; collagen type XI alpha 2; collagen type XI alpha 2 chain; collagen XI-like; collagen, type XI, alpha 2; DAQB-79P13.8; DFNA13; DFNB53; FBCG2; HGNC:2187; HKE5; PARP; pro-a2 chain of collagen type XI; procollagen, type XI, alpha 2; putative collagen XI; STL3; type XI collagen alpha2 chain
Gene Symbols COL11A2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 1200-1250 of Human COL11A2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12815, 1302
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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