Invitrogen™ COL15A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551288

Catalog No. PA551288

Description

The antibody detects endogenous levels of total COL15A1 protein.

This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.

Specifications

• Antigen: COL15A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COL15A1
• Gene Alias: COFA1; COL15A1; Collagen alpha-1(XV) chain; collagen type XV alpha 1 chain; collagen type XV proteoglycan; collagen XV, alpha-1 polypeptide; collagen, type XV, alpha 1; endostatin-XV; procollagen type XV; procollagen, type XV; Related to endostatin; Restin; Restin-2; Restin-3; Restin-4; Restin-I; Restin-II; Restin-III; Restin-IV; type XV collagen
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1306
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 2.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P39059
• Gene Symbols: COL15A1
• Immunogen: Synthetic peptide of human COL15A1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov