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Invitrogen™ COL21A1 Polyclonal Antibody
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Catalog No. PIPA545317
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100 μL
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PIPA545317 100 μL
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Catalog No. PIPA545317 Supplier Invitrogen™ Supplier No. PA545317
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Description

Rabbit Polyclonal Antibody

Peptide sequence: PGEPGYMGLP GIQGKKGDKG NQGEKGIQGQ KGENGRQGIP GQQGIQGHHG Sequence homology: Dog: 93%; Horse: 100%; Human: 100%; Pig: 100%.

COL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein, and a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. COL17A1 is a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Moreover, COL17A1 is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COL21A1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene COL21A1
Gene Accession No. Q96P44
Gene Alias alpha 1 chain-like collagen; COL1AL; COL21A1; COLA1L; Collagen alpha-1(XXI) chain; collagen type XXI alpha 1 chain; collagen, type XXI, alpha 1; FP633
Gene Symbols COL21A1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human COL21A1 (aa 682-731).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 81578
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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