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Invitrogen™ COL21A1 Polyclonal Antibody
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Catalog No. PIPA556675
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100 μL
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PIPA556675 100 μL
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Catalog No. PIPA556675 Supplier Invitrogen™ Supplier No. PA556675
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Rabbit Polyclonal Antibody

Immunogen sequence: AKSSRFLTKI AVVLTDGKSQ DDVKDAAQAA RDSKITLFAI GVGSETEDAE LRAIANKPSS TYVFYVEDYI AISKIREVMK Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 45%.

COL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein, and a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. COL17A1 is a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Moreover, COL17A1 is localized to tissues containing type I collagen so, like other members of this collagen family, it may serve to maintain the integrity of the extracellular matrix. Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COL21A1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene COL21A1
Gene Accession No. Q96P44
Gene Alias alpha 1 chain-like collagen; COL1AL; COL21A1; COLA1L; Collagen alpha-1(XXI) chain; collagen type XXI alpha 1 chain; collagen, type XXI, alpha 1; FP633
Gene Symbols COL21A1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human COL21A1. Recombinant protein control fragment (Product #RP-94805).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 81578
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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