Invitrogen™ COL22A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570816

Catalog No. PIPA570816

Description

This target displays homology in the following species: Cow: 92%; Dog: 79%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%.

This gene encodes member of the collagen family which is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction which is present only at the tissue junctions of muscles, tendons, the heart, articular cartilage, and skin. A knockdown of the orthologous zebrafish gene induces a muscular dystrophy by disruption of the myotendinous junction.

Specifications

• Antigen: COL22A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COL22A1
• Gene Alias: 2310067L16Rik; C80743; COL22A1; Collagen alpha-1(XXII) chain; collagen type XXII alpha 1; collagen type XXII alpha 1 chain; collagen, type XXII, alpha 1; procollagen, type XXII, alpha 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 169044
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8NFW1
• Gene Symbols: COL22A1
• Immunogen: synthetic peptide directed towards the N-terminal region of human COL22A1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG