Invitrogen™ COL4A6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550939

Catalog No. PA550939

Description

COL4A6 Polyclonal Antibody detects endogenous levels of COL4A6 protein.

Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Specifications

• Antigen: COL4A6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COL4A6
• Gene Alias: BB116301; Col4a6; Collagen 4; Collagen alpha-6(IV) chain; collagen IV, alpha-6 polypeptide; collagen of basement membrane, alpha-6; collagen type IV alpha 6 chain; collagen, type IV, alpha 6; CXDELq22.3; DELXq22.3; DFNX6; dJ889N15.4 (Collagen Alpha 6(IV)); procollagen type IV alpha 6; procollagen, type IV, alpha 6
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1288, 363458, 94216
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q14031
• Gene Symbols: COL4A6
• Immunogen: Synthesized peptide derived from the C-terminal region of human COL4A6.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG