Invitrogen™ COL5A3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144797

Catalog No. FEPA5144797

Description

Immunogen sequence: STDIPKTETP APNLPPTPTP LVVTSTVTTG LNATILEGSL DPDSGTELGT LETKAAREDE EGDDSTMGPD FRAAEYPSRT QFQ Antigen sequence identity: Mouse 52%; Rat 55%.

Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Specifications

• Antigen: COL5A3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COL5A3
• Gene Alias: COL5A3; Collagen 5; Collagen alpha-3(V) chain; collagen type V alpha 3; collagen, type V, alpha 3; collagen, type V, alpha 4; pro-(alpha)3(V) collagen; Pro-alpha3(V); procollagen, type V, alpha 3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50509
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P25940
• Gene Symbols: COL5A3
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 285-367. Recombinant protein control fragment (Product #RP-98883).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid