Invitrogen™ COL7A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103378

Catalog No. PIPA5103378

Description

Antibody detects endogenous levels of total Collagen VII alpha 1.

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008].

Specifications

• Antigen: COL7A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COL7A1
• Gene Alias: alpha-1 type VII collagen; AW209154; COL7A1; collagen alpha-1(VII) chain; collagen type VII alpha 1; collagen type VII alpha 1 chain; collagen vii; collagen VII, alpha-1 polypeptide; collagen, type VII, alpha 1; EBD1; EBDCT; EBR1; HGNC:2214; LC collagen; long chain collagen; long-chain collagen; NDNC8; procollagen, type VII, alpha 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12836, 1294
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q02388, Q63870
• Gene Symbols: COL7A1
• Immunogen: A synthesized peptide derived from human COL7A1(Accession Q02388), corresponding to amino acid residues E2851-T2901.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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