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Invitrogen™ COL9A1 Polyclonal Antibody
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Catalog No. PIPA584959
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100 μL
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PIPA584959 100 μL
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Catalog No. PIPA584959 Supplier Invitrogen™ Supplier No. PA584959
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PIKPRGPIDI DGFAVLGKLA DNPQVSVPFE LQWMLIHCDP LRPRRETCHE LPARITPSQT TDERGPPGEQ GPP Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 93%.

COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COL9A1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene COL9A1
Gene Accession No. P20849
Gene Alias alpha 1 type IX collagen; alpha-1(IX) collagen chain; cartilage-specific short collagen; COL9A1; Col9a-1; Collagen alpha-1(IX) chain; collagen IX, alpha-1 polypeptide; collagen type IX alpha 1; collagen, type IX, alpha 1; DJ149L1.1.2; EDM6; MED; procollagen, type IX, alpha 1; STL4
Gene Symbols COL9A1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human COL9A1. Recombinant protein control fragment (Product #RP-108640).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1297
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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