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Collagen 11 alpha 2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985014
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50-198-5014 100 μL
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Catalog No. 50-198-5014 Supplier Bioss Supplier No. BS2924R
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Description

Rabbit Polyclonal Antibody

This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.

Specifications

Antigen Collagen 11 alpha 2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene COL11A2
Gene Accession No. P13942
Gene Alias BOS_21301; Col11a2; Collagen alpha-2(XI) chain; collagen type XI alpha 2; collagen XI-like; collagen, type XI, alpha 2; DAQB-79P13.8; DFNA13; DFNB53; FBCG2; HGNC:2187; HKE5; LOC100008787; PARP; pro-a2 chain of collagen type XI; procollagen, type XI, alpha 2; putative collagen XI; STL3; type XI collagen alpha2 chain
Gene Symbols COL11A2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human COL11A2 COLFI domain.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1302
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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