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Invitrogen™ COMMD10 Polyclonal Antibody
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Catalog No. PIPA5140077
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100 μL
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PIPA5140077 100 μL
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Catalog No. PIPA5140077 Supplier Invitrogen™ Supplier No. PA5140077
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: SLEKQDLHLV LETISFILEQ AVYHNVKPAA LQQQLENIHL RQDKAEAFVN TWSSMGQ Highest antigen sequence indentity to the following orthologs: Rat - 84%, Mouse - 86%.

The COMMD family represents a group of evolutionary conserved proteins that share a common COMM domain at their extreme C-terminus, which provides an interface for protein-protein interactions. COMMD10 (COMM domain containing 10), also known as PTD002 or HSPC305, is a 202 amino acid protein that belongs to the COMMD family and contains one COMM domain. The gene encoding COMMD10 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COMMD10
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene COMMD10
Gene Accession No. Q9Y6G5
Gene Alias 2310003A05Rik; AU019438; COMM domain containing 10; COMM domain-containing protein 10; COMMD10; Down-regulated in W/WV mouse stomach 2; DRWMS2; HSPC305; mDRWMS2; PTD002
Gene Symbols COMMD10
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human COMMD10. Recombinant protein control fragment (Product #RP-108056).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51397
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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