Invitrogen™ COMMD5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595782

Catalog No. PIPA595782

Description

Immunogen sequence: MSAVGAATPY LHHPGDSHSG RVSFLGAQLP PEVAAMARLL GDLDRSTFRK LLKFVVSSLQ GEDCREAVQR LGVSANLPEE QLGALLAGMH TLLQQALRLP PTSLKPDTFR DQLQELCIPQ DLVGDLASVV FGSQRPLLDS VAQQQGAWLP HVADFRWRVD VAISTSALAR SLQPSVLMQL KLSDGSAYRF EVPTAKFQEL RYSVALVLKE MADLEKRCER RLQD; Positive Samples: SGC996, 293T, LO2, HeLa, A-431, Mouse kidney, Rat liver; Cellular Location: Cytoplasm, Nucleus.

COMMD5 is a protein coding gene. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.

Specifications

• Antigen: COMMD5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COMMD5
• Gene Alias: 2310065H03Rik; AI854466; COMM domain containing 5; COMM domain-containing protein 5; COMMD5; D15Ertd81e; FLJ13008; HCARG; HT002; hypertension-related calcium regulated; hypertension-related calcium-regulated gene protein; hypertension-related, calcium regulated
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 245974, 28991, 66398
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.48 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q8R395, Q9ERR2, Q9GZQ3
• Gene Symbols: COMMD5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human COMMD5 (NP_0547852).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov