Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 01674417

Invitrogen™ Complement C4b Polyclonal Antibody
GREENER_CHOICE

Catalog No. 01674417
Change view
Click to view available options
Quantity:
500 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
01-674-417 500 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 01-674-417 Supplier Invitrogen™ Supplier No. PA19534
Only null left
Add to Cart
Add to Cart

Description

Chicken Polyclonal Antibody

PA1-9534 detects C4b complement in human samples. PA1-9534 has been successfully used in Western blot and ELISA procedures. By Western blot, PA1-9534 detects a 88 Kda, 75 Kda, 33 Kda protein representing C4b complement. PA1-9534 immunogen is a purified human C4b complement protein. Store product at 4ºC for up to one week and -20ºC for long-term.

This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Complement C4b
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene C4B
Gene Accession No. P0C0L5
Gene Alias Acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; c4 complement; C4A; C4a anaphylatoxin; C4A13; C4A91; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4d-A; C4d-B; C4F; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement C4-B-like; complement component 4B (Chido blood group); complement component 4B (Chido blood group), copy 2; CPAMD2; CPAMD3; DADB-112B14.11; FLJ60561; MGC164979
Gene Symbols C4B, C4B_2
Host Species Chicken
Immunogen Purified human C4b complement protein.
Purification Method IgY fraction
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100293534, 721
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgY
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.