MilliporeSigma™ Complement C5a des-Arg, Human, Protein

Description

Native, human des-Arg C5a complement component. Single chain glycopeptide composed of 73 amino acids. Once the C5a glycopeptide has been produced in human plasma or serum, it is rapidly converted to C5a des-Arg upon removal of the C-terminal arginine by the endogenous serum carboxypeptidase N. Unlike the C3a des-Arg peptide, C5a des-Arg retains significant levels of its biological activities. Thus, C5a des-Arg has been shown to exhibit inflammatory cell chemotaxis, smooth muscle contraction, and leukotriene release from guinea pig lung.

Specifications

• Concentration: Concentration on Label
• Formulation: In 120mM NaCl, 10mM HEPES, pH 7.2.
• Purification Method: SDS-PAGE
• Quantity: 30 μg
• Immunogen: Complement C5a des-Arg
• Storage Requirements: Following initial thaw, aliquot and freeze (−70°C).
• Regulatory Status: RUO
• Species: Human
• Recombinant: Native
• Form: Liquid
• Purity or Quality Grade: ≥90%