Invitrogen™ Complement Factor B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527924

Catalog No. PIPA527924

Description

Recommended positive controls: Raji, K562, Rat liver. Predicted reactivity: Mouse (84%), Rat (85%), Chimpanzee (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Factor B is a component of the alternative complement pathway. The protein is a single chain polypeptide with a molecular mass of 93 kDa. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Bb together with C3b forms the alternative pathway C3 convertase C3bBb.

Specifications

• Antigen: Complement Factor B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CFB
• Gene Alias: AHUS4; AI195813; AI255840; alternative-complement pathway C3/C5 convertase; ARMD14; B; BF; B-factor, properdin; BFD; C2; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; complement component 2 (within H-2S); complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; Da1-24; DADB-122G4.5; Factor B; Fb; FBI12; GBG; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; histocompatibility 2, complement component factor B; PBF2; properdin; properdin factor B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14962, 294257, 629
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.87 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P00751, P04186
• Gene Symbols: CFB
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Factor B. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov