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R&D Systems™ Compound E
SDP

Catalog No. RD10188119 Shop All Novus Products
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Catalog No.
RD10188119 5 mg
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Catalog No. RD10188119 Supplier R&D Systems™ Supplier No. TB6476RMU/5

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Description

A Tocris product, part of R&D Systems.

Compound E is a γ-secretase and notch pathway inhibitor. Compound E enhances growth inhibition, differentiation and migration of neuroblastoma cells when used in a combination with DAPT (Cat. No. 2634) and 13-cis RA. In combination with hLIF, CHIR 99021 (Cat. No. 4423) and SB 431542 (Cat. No. 1614), Compound E accelerates the induction of a homogeneous, self-renewing primitive neuroepithelium population from hESCs. Compound E is active in vitro and in vivo. Used in protocol to generate pancreatic beta cells from hPSCs (see below).

For more information about how Compound E may be used, see our protocol: Generation of β cells from hPSCs

This product is Bio-Techne's ancillary Material Grade version of Compound E (Cat. No. 6476). Suitable for use in research and further manufacturing of cell therapies. Find out more about our Ancillary Material Grade product range.

Specifications

Chemical Name or Material N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
CAS 209986-17-4
Quantity 5 mg
Product Line Tocris
Target Ancillary Material Grade Compounds
Molecular Formula C27H24F2N4O3
Purity 98%
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