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Invitrogen™ COMT Monoclonal Antibody (630CT1.7.1)
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Catalog No. PIMA537612
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100 μL
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Catalog No. Quantity
PIMA537612 100 μL
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Catalog No. PIMA537612 Supplier Invitrogen™ Supplier No. MA537612
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Description

Mouse Monoclonal Antibody

COMT Monoclonal Antibody for Western Blot

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COMT
Applications Western Blot
Classification Monoclonal
Clone 630CT1.7.1
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.09% sodium azide; pH 7.4
Gene Comt
Gene Accession No. P21964
Gene Alias Catechol O-methyltransferase; catecholamine-O-methyltransferase; catechol-O-methyltransferase; catechol-O-methyltransferase 1; catechol-O-methyltransferase isoform; Comt; Comt1; D16Wsu103e; D330014B15Rik; epididymis secretory sperm binding protein Li 98n; HEL-S-98n; OTTHUMP00000197749; OTTHUMP00000197750; testicular tissue protein Li 42
Gene Symbols Comt
Host Species Mouse
Immunogen KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human COMT.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1312
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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