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  5. Tocris Bioscience™ Conduritol B epoxide

Tocris Bioscience™ Conduritol B epoxide
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Catalog No. 705625
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Irreversible glucocerebrosidase (β-glucosidase) inhibitor; used to generate Gaucher disease models

Conduritol B epoxide is an irreversible glucocerebrosidase (GBA) inhibitor (Ki = 53 μM; IC50 = 4.28 - 9.49 μM). Also inhibitis lysosomal α-glucosidase. Used to generate animal models of Gaucher disease. Accelerates recovery of peripheral nerve injury in mice. Preserves motoneurons and ganglioside distribution at the neuromuscular junction, delays disease onset and improves motor function in a mouse ALS model.

Specifications

Chemical Name or Material DL-1,2-Anhydro-myo-Inositol
CAS 6090-95-5
Quantity 25 mg
Target Glycosylase Inhibitors
Molecular Formula C6H10O5
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