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Invitrogen™ Connexin 26 Polyclonal Antibody
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Catalog No. PIPA518618
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100 μg
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Catalog No. Quantity
PIPA518618 100 μg
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Catalog No. PIPA518618 Supplier Invitrogen™ Supplier No. PA518618
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with human and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variables (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Connexin 26
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Gjb2
Gene Accession No. P21994, P29033, Q00977
Gene Alias AI325222; Cnx26; connexin 26; connexin-26; CX26; CXN-26; DFNA3; DFNA3A; DFNB1; DFNB1A; Gap junction beta-2 protein; gap junction channel protein connexin 26; gap junction membrane channel protein beta 2; gap junction protein beta 2; gap junction protein, beta 2; gap junction protein, beta 2, 26kDa; GJB2; Gjb-2; HID; KID; mutant gap junction protein beta 2; NSRD1; PPK
Gene Symbols Gjb2
Host Species Goat
Immunogen Synthetic peptide sequence (YLLIRYCSGKSKKP) corresponding to the C-terminus amino acids of GJB2 (aa 212-225).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14619, 2706, 394266
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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