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Invitrogen™ Connexin 26 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ 512800

Description
Connexin 26 Polyclonal Antibody for Western Blot, ICC/IF, IHC (F), IHC (P), ELISA
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variables (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
Specifications
Connexin 26 | |
Polyclonal | |
Unconjugated | |
Gjb2 | |
AI325222; Cnx26; connexin 26; connexin-26; CX26; CXN-26; DFNA3; DFNA3A; DFNB1; DFNB1A; Gap junction beta-2 protein; gap junction channel protein connexin 26; gap junction membrane channel protein beta 2; gap junction protein beta 2; gap junction protein, beta 2; gap junction protein, beta 2, 26kDa; GJB2; Gjb-2; HID; KID; mutant gap junction protein beta 2; NSRD1; PPK | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
14619, 2706, 394266 | |
-20°C | |
Liquid |
ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.25 mg/mL | |
PBS with 0.1% sodium azide; pH 7.4 | |
P21994, P29033, Q00977 | |
Gjb2 | |
A 13 amino acid synthetic peptide derived from the C-terminus of the mouse Connexin 26 protein. This mouse sequence differs from the rat sequence by a single amino acid and from the human sequence by two (non-consecutive) amino acids. | |
50 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
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