Invitrogen™ Connexin 30 Monoclonal Antibody (CL4540)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA535021

Catalog No. PIMA535021

Description

Immunogen sequence: RSKRAQTQKN HPNHALKESK.

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.

Specifications

• Antigen: Connexin 30
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95452
• Gene Symbols: GJB6
• Immunogen: Synthetic Peptide corresponding to Human Connexin 30.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunocytochemistry
• Clone: CL4540
• Conjugate: Unconjugated
• Gene: GJB6
• Gene Alias: AA958971; connexin 30; connexin-30; CX30; Cxn-30; D14Bwg0506e; DFNA3; DFNA3B; DFNB1B; ECTD2; ectodermal dysplasia 2, hidrotic (Clouston syndrome); ED2; EDH; Gap junction beta-6 protein; gap junction membrane channel protein beta 6; gap junction protein beta 6; gap junction protein, beta 6; gap junction protein, beta 6 (connexin 30); gap junction protein, beta 6, 30kDa; Gjb6; HED; HED2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10804
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid