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Invitrogen™ Connexin 30 Monoclonal Antibody (CL4540)
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Catalog No. PIMA535021
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100 μL
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Catalog No. Quantity
PIMA535021 100 μL
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Catalog No. PIMA535021 Supplier Invitrogen™ Supplier No. MA535021
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Description

Mouse Monoclonal Antibody

Immunogen sequence: RSKRAQTQKN HPNHALKESK Highest antigen sequence indentity to the following orthologs: Rat - 85%, Mouse - 85%.

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Connexin 30
Applications Immunocytochemistry
Classification Monoclonal
Clone CL4540
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GJB6
Gene Accession No. O95452
Gene Alias AA958971; connexin 30; connexin-30; CX30; Cxn-30; D14Bwg0506e; DFNA3; DFNA3B; DFNB1B; ECTD2; ectodermal dysplasia 2, hidrotic (Clouston syndrome); ED2; EDH; Gap junction beta-6 protein; gap junction membrane channel protein beta 6; gap junction protein beta 6; gap junction protein, beta 6; gap junction protein, beta 6 (connexin 30); gap junction protein, beta 6, 30kDa; Gjb6; HED; HED2
Gene Symbols GJB6
Host Species Mouse
Immunogen Synthetic Peptide corresponding to Human Connexin 30.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10804
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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