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Invitrogen™ Connexin 31 Polyclonal Antibody
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Catalog No. PIPA5113757
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PIPA5113757 100 μL
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Catalog No. PIPA5113757 Supplier Invitrogen™ Supplier No. PA5113757
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Rabbit Polyclonal Antibody

Immunogen sequence: MDWKKLQDLL SGVNQYSTAF GRIWLSVVFV FRVLVYVVAA ERVWGDEQKD For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 79%; Dog: 83%; Horse: 83%; Human: 83%; Mouse: 100%; Pig: 83%; Rabbit: 79%; Rat: 100%; Zebrafish: 92%.

Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Connexin 31
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene GJB3
Gene Accession No. P28231
Gene Alias Cnx31; connexin 31; connexin-31; Cx31; Cxn-31; D4Wsu144e; DFNA2; DFNA2B; EKV; Gap junction beta-3 protein; gap junction membrane channel protein beta 3; gap junction protein beta 3; gap junction protein, beta 3; gap junction protein, beta 3, 31kDa; Gjb3; Gjb-3
Gene Symbols GJB3
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal region of Mouse Gjb3 (aa 1-50).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14620
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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