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Connexin 40 Recombinant Polyclonal Antibody (5HCLC), Invitrogen™

Catalog No. PI710226
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100 μg
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PI710226 100 μg
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Catalog No. PI710226 Supplier Thermo Scientific Supplier No. 710226

Rabbit Recombinant Polyclonal Antibody

This antibody is predicted to react with equine, mouse and rat based on sequence homology. Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

Connexin 40 (Cx40), belongs to the connexin family of gap junction proteins, which are expressed in pancreas, kidney, skeletal muscle, liver, placenta and heart. Connexin 40 is highly expressed in vascular endothelial cells, and the mammalian heart (specifically in the atrial myocardium, and the His-Purkinje conduction system). At least three other connexins are expressed in the heart, including Cx37 (endocardium), Cx43 (atrial and ventricular myocardium, and distal parts of the conduction system) and Cx45 (throughout the heart). Cx40 and Cx43 frequently co-localize in cells of the cardiovascular system and participate in the formation of heterotypic gap junction channels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Connexin 40
Applications Immunocytochemistry
Classification Recombinant Polyclonal
Clone 5HCLC
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene Gja5
Gene Accession No. P36382
Gene Alias 5730555N10Rik; ATFB11; Cnx40; connexin 40; connexin-40; Cx40; Cxn-40; Gap junction alpha-5 protein; gap junction membrane channel protein alpha 5; gap junction protein; gap junction protein alpha 5; gap junction protein alpha 5 40kDa; gap junction protein, alpha 5; GJA5; Gja-5
Gene Symbols Gja5
Host Species Rabbit
Immunogen Peptide corresponding to amino acids 334–344 of human connexin 40
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2702
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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