Invitrogen™ Connexin 50 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA584575

Catalog No. PIPA584575

Description

Immunogen sequence: VHYVRMEEKR KSREAEELGQ QAGTNGGPDQ GSVKKSSGSK GTKKFRLEGT LL.

This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.

Specifications

• Antigen: Connexin 50
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GJA8
• Gene Alias: Aey5; alpha 8 connexin; CAE; CAE1; cell surface glycoprotein; Cnx50; connexin 50; connexin-49; Connexin-50; CTRCT1; cx49; CX50; CZP1; gap junction alpha 8; gap junction alpha-8 protein; gap junction membrane channel protein alpha 8; gap junction membrane channel protein alpha-8; gap junction protein alpha 8; gap junction protein alpha 8 50kDa; gap junction protein, alpha 8; gap junction protein, alpha 8, 50kDa; GJA8; Lens fiber protein MP70; lens intrinsic membrane protein MP70; lens opacity 10; Lop10; MP38; MP64; MP70
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2703
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P48165
• Gene Symbols: GJA8
• Immunogen: Recombinant protein corresponding to Human GJA8. Recombinant protein control fragment (Product #RP-108480).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG