Invitrogen™ Connexin 50 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA511644

Catalog No. PIPA511644

Description

This antibody is predicted to react with chicken based on sequence homology.

This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.

Specifications

• Antigen: Connexin 50
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GJA8
• Gene Alias: Aey5; alpha 8 connexin; CAE; CAE1; cell surface glycoprotein; Cnx50; connexin 50; connexin-49; Connexin-50; CTRCT1; cx49; CX50; CZP1; gap junction alpha 8; gap junction alpha-8 protein; gap junction membrane channel protein alpha 8; gap junction membrane channel protein alpha-8; gap junction protein alpha 8; gap junction protein alpha 8 50kDa; gap junction protein, alpha 8; gap junction protein, alpha 8, 50kDa; GJA8; Lens fiber protein MP70; lens intrinsic membrane protein MP70; lens opacity 10; Lop10; MP38; MP64; MP70
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 14616, 2703
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.6 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P28236, P48165
• Gene Symbols: GJA8
• Immunogen: KLH conjugated synthetic peptide between 402-433 amino acids from the C-terminal region of human Connexin 50.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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