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Invitrogen™ Contactin 2 Polyclonal Antibody
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Catalog No. PIPA5101541
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PIPA5101541 100 μL
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Catalog No. PIPA5101541 Supplier Invitrogen™ Supplier No. PA5101541
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CNTN2.

Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunoglobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Contactin 2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CNTN2
Gene Accession No. P22063, Q02246, Q61330
Gene Alias Axonal glycoprotein TAG-1; axonin; Axonin 1; Axonin1; axonin-1; axonin-1 cell adhesion molecule; AXT; Cntn2; contactin 2; contactin 2 (axonal); contactin 2 (transiently expressed); Contactin2; contactin-2; D130012K04Rik; DKFZp781D102; FAME5; MGC157722; TAG1; TAG-1; TAG-564; Tax; TAX1; TAX-1; transient axonal glycoprotein 1; transiently-expressed axonal glycoprotein
Gene Symbols CNTN2
Host Species Rabbit
Immunogen A synthesized peptide derived from human CNTN2(Accession Q02246), corresponding to amino acid residues S114-L164.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21367, 25356, 6900
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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