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Invitrogen™ Contactin 2 Recombinant Rabbit Monoclonal Antibody (4R2S3)
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Catalog No. PIMA542873
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100 μL
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PIMA542873 100 μL
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Catalog No. PIMA542873 Supplier Invitrogen™ Supplier No. MA542873
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: A-549, C6, SH-SY5Y, U-251MG, Mouse lung, Mouse spinal cord, Mouse brain, Rat brain. The target is usually found in the following locations: Cell membrane, GPI-anchor, Lipid-anchor. Immunogen sequence: MGTATRRKPH LLLVAAVALV SSSAWSSALG SQTTFGPVFE DQPLSVLFPE ESTEEQVLLA CRARASPPAT YRWKMNGTEM KLEPGSRHQL VGGNLVIMNP.

Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunoglobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Contactin 2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 4R2S3
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CNTN2
Gene Accession No. Q02246, Q61330
Gene Alias Axonal glycoprotein TAG-1; axonin; Axonin 1; Axonin1; axonin-1; axonin-1 cell adhesion molecule; AXT; Cntn2; contactin 2; contactin 2 (axonal); contactin 2 (transiently expressed); Contactin2; contactin-2; D130012K04Rik; DKFZp781D102; FAME5; MGC157722; TAG1; TAG-1; TAG-564; Tax; TAX1; TAX-1; transient axonal glycoprotein 1; transiently-expressed axonal glycoprotein
Gene Symbols CNTN2
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21367, 6900
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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