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COPS2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988840
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100 μL
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50-198-8840 100 μL
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Catalog No. 50-198-8840 Supplier Bioss Supplier No. BS9125R
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Rabbit Polyclonal Antibody

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

Antigen COPS2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CSN2
Gene Accession No. P05814, P61201
Gene Alias AI315723; alien; Alien homolog; Alien protein; alien-like; alien-PA; alien-PB; alien-PD; alien-PE; BcDNA:LD10463; Beta-casein; C85265; CASB; casein beta; CG9556; CG9556 gene product from transcript CG9556-RD; CG9556-PA; CG9556-PB; CG9556-PD; CG9556-PE; CH2; COP9; COP9 (constitutive photomorphogenic) homolog, subunit 2; COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana); COP9 complex homolog subunit 2; COP9 constitutive photomorphogenic homolog subunit 2; COP9 signalosome complex subunit 2; COP9 signalosome subunit 2; COPS2; CSN2; Csnb; d-Alien; Dch2; Dmel\CG9556; Dmel_CG9556; drosophila COP9 signalosome homolog 2; JAB1-containing signalosome subunit 2; SGN2; signalosome subunit 2; thyroid receptor interacting protein 15; Thyroid receptor-interacting protein 15; TR-interacting protein 15; Trip15; TRIP-15; tyroid receptor interacting protein 15
Gene Symbols COPS2, CSN2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human COPS2/TRIP15.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1447, 9318
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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